Stephen Tobin

Stephen Tobin

Associate Professor



1987 - B.S., University of Notre Dame, Biochemistry
1999 - Ph.D., Dartmouth College, Biochemistry

My research interests include the desire to better understand how alterations of cellular signaling cascades contribute to the development of breast cancer.

My research background includes the study of one of the most versatile and potent growth-regulatory proteins, Transforming Growth Factor-b (TGF-b). My efforts have been directed at elucidation of the role of TGF-b signaling in tumor formation and progression to metastatic disease. In addition, these studies focused on identification of potential molecular mechanisms by which the TGF-b pathway influences cellular susceptibility to the cytotoxic effects of Tumor Necrosis Factor-a, a cytokine produced by cells of the immune system.